Syndrome of Inappropriate Antidiuretic Hormone Secretion (SIADH)

  1. General information
    1. Hypersection of ADH from the posterior pituitary gland even when the client has abnormal serum osmolality.
    2. SIADH may occur in persons with bronchogenic carcinoma or other nonendocrine conditions.
  2. Medical management
    1. Treat underlying cause if possible
    2. Diuretics and fluid restriction
  3. Assessment findings
    1. Persons with SIADH cannot excrete a dilute urine
    2. Fluid retention and sodium deficiency.
  4. Nursing interventions
    1. Administer diuretics (furosemide [Lasix]) as ordered
    2. Restrict fluids to promote fluid loss and gradual increase in serum sodium.
    3. Monitor serum electrolytes and blood chemistries carefully
    4. Careful intake and output, daily weight
    5. Monitor neurologic status

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