Non-Hodgkin's Lymphoma

  1. General information
    1. Tumor originating in lymphatic tissue
    2. Significantly different from Hodgkin's lymphoma
      1. Control of primary tumor is difficult
      2. Disease is diffuse, cell type undifferentiated
      3. Tumor disseminates early
      4. Includes wide range of disease entities: lymphosarcoma, reticulum cell sarcoma, Burkitt's lymphoma
    3. Primary sites include GI tract, ovaries, testes, bone, CNS, liver, breast, subcutaneous tissues
    4. Affects all age groups.
  2. Medical management
    1. Chemotherapy: multiagent regimens including cyclophosphamide (Cytoxan), vincristine, prednisone, procarbazine, doxorubicin, bleomycin
    2. Radiation therapy: primary treatment in localized disease
    3. Surgery for diagnosis and clinical staging
  3. Assessment findings
    1. Depend on anatomic site and extent of involvement
    2. Rapid onset and progression
    3. Many have advanced disease at diagnosis
  4. Nursing interventions: provide care for child receiving chemotherapy, radiation therapy, and surgery.

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