NONSTEROIDAL ANTI-INFLAMMATORY DRUGS

> NSAIDs inhibit prostaglandin synthesis and may cause erosive gastritis and bleeding. Discourage "routine" use.


Major side effects
Nursing Interventions
aspirin
GI distress, occult bleeding suppresses platelet function may cause Raye's syndrome
-give with meals or milk
-dont give within 1 week of surgery (risk of bleeding)
-dont give with children with viral infection

acetaminophen
liver toxicity with overdose
-monitor liver enzymes for 1 week in case of overdose

ibuprofen
GI distress
-give with meals or milk

phenylbytazone
bone marrow depression, anemia
-monitor CBC
-should not be used for more than 1 week

indomethacin
CNS: dizziness, lightheadedness, blurred vision
-regular eye exam if used for long term therapy


signs of salicylate intoxications:
mild- tinnitus, central hyperventilation
severe- respiratory plus metabolic acidosis

Reye's syndrome:
avoid aspirin in children with viral infection
rish for fulminant hepatitis, cerebral edema
-Haunurses 5/14/08 3:42 PM

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