ANTICOAGULANTS


Antagonist (in case of Overdose) Nursing Interventions
heparin (immediate effect) protamine sulfate -do not give IM(hematoma and pain) -watch for bleeding, bruises -teach client to avoid aspirin -monitor partial thromboplastin time (PTT)
warfarin (takes 4-5 days for full effect) oral vitamin k -watch for bleeding, bruises -teach client to avoid aspirin -if ongoing therapy: client should carry medical alert card -monitor prothrombin time (PT)
streptokinase, urokinase (to dissolve thrombi) aminocaproic acid -risk of severe bleeding have blood available for transfusion

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