NONSTEROIDAL ANTI-INFLAMMATORY DRUGS
> NSAIDs inhibit prostaglandin synthesis and may cause erosive gastritis and bleeding. Discourage "routine" use.
| Major side effects | Nursing Interventions | |
| aspirin | GI distress, occult bleeding suppresses platelet function may cause Raye's syndrome | -give with meals or milk -dont give within 1 week of surgery (risk of bleeding) -dont give with children with viral infection |
| acetaminophen | liver toxicity with overdose | -monitor liver enzymes for 1 week in case of overdose |
| ibuprofen | GI distress | -give with meals or milk |
| phenylbytazone | bone marrow depression, anemia | -monitor CBC -should not be used for more than 1 week |
| indomethacin | CNS: dizziness, lightheadedness, blurred vision | -regular eye exam if used for long term therapy |
signs of salicylate intoxications:
mild- tinnitus, central hyperventilation
severe- respiratory plus metabolic acidosis
Reye's syndrome:
avoid aspirin in children with viral infection
rish for fulminant hepatitis, cerebral edema
-Haunurses 5/14/08 3:42 PM
Wednesday, May 14, 2008
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Labels:
Pharmacology
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