Angelite Nurses: ANTICOAGULANTS

	Antagonist (in case of Overdose)	Nursing Interventions
heparin (immediate effect)	protamine sulfate	-do not give IM(hematoma and pain) -watch for bleeding, bruises -teach client to avoid aspirin -monitor partial thromboplastin time (PTT)
warfarin (takes 4-5 days for full effect) oral	vitamin k	-watch for bleeding, bruises -teach client to avoid aspirin -if ongoing therapy: client should carry medical alert card -monitor prothrombin time (PT)
streptokinase, urokinase (to dissolve thrombi)	aminocaproic acid	-risk of severe bleeding have blood available for transfusion

Angelite Nurses