Drug Administration

Basic Critical Thinking Guidelines for Safe Drug Administration

Before administration:

      • gather general baseline data
        • VS, lab results, allergies, co-morbidities, Ht, Wt; liver, pulmonary, renal, neuro, nutrition, hydration status
      • identify client factors
        • affects on drug action from age, cultural factors, history
      • determine purpose of therapy
        • indication for drug; desired therapeutic outcome
      • reconcile medication profile
        • with client, family, nursing staff, provider
      • verify prescription and client
        • dose, time, calculations, dosing range, dispensing method

After administration:

      • monitor client response
        • therapeutic effect, adverse effects, toxicity
      • document findings and act
        • data requiring action or follow-up nursing care
      • document nursing care
        • describe: care before and after, drug administration
      • evaluate care and process
        • describe: med errors, problems so others, agency benefit

Client teaching

      • instruct client and family about drug
        • what to report; how to administer; food, substances, activities to avoid; need for follow-up care and testing

Basic Nursing Care to Prevent or Minimize Common Adverse Effects of Drug Therapy

  • Adverse effect: nursing care, monitoring, teaching
    • nausea, vomiting, anorexia
      • collaborate for antiemetic, eliminate triggers, maintain NPO status
      • monitor F/E balance, bowel sounds and pattern, food intake
      • teaching: small, frequent meals, breathing techniques; avoid triggers
    • constipation
      • provide fluid, fiber, stool softener, encourage ambulation
      • monitor bowel sounds, pattern; review diet for fluid, fiber
      • teaching: increase fluid, fiber; ambulate; establish bowel habits
    • diarrhea
      • provide hygiene, skin care, close supervision to prevent injury
      • monitor bowel pattern, F/E balance, weakness, skin, cultures
      • teaching: increase fluid intake, wash hands, avoid irritating foods
    • rash, allergy
      • screen for allergies, previous reactions, provide skin care
      • monitor airway, breathing, BP, skin, pruritus, cultures
      • teaching: report dypsnea, pruritus, hives, worsening condition
    • hypotension, dizziness
      • maintain supine position, encourage fluids, review med profile
      • monitor VS, Sa02, EKG, level of consciousness, U/O
      • teaching: remain in bed; ask for help to stand; avoid alcohol, sedation

Basic Nursing Care to Prevent or Minimize Adverse Effects of a Drug Class or Type

  • Drug class or type with related adverse effects: nursing care, monitoring, and teaching
    • antihypertensives: orthostatic hypotension, F/E imbalance
      • assist with activity; eliminate drug interactions, vasodilators, CNS depressants
      • monitor BP, pulse, breath sounds, serum electrolyte levels, edema, dizziness
      • teaching: get help to stand, report dizziness; avoid alcohol, sedatives, OTC agents, caffeine
    • anticholinergic agents: dry mouth, constipation, blurred vision
      • provide sips of water, oral care; assist with activity; remove environmental hazards
      • monitor bowel pattern, vision, oral mucous membranes
      • teaching: frequent oral care, avoid dangerous activity, ask for help to stand
    • anticoagulants and antiplatelet agents: bleeding
      • minimize invasive procedures, shaving; provide gentle oral care; assist with activity
      • monitor bleeding, coagulation tests, CBC, bruising; remove adverse drug and food affects
      • teaching: avoid dangerous activity, wear Medic alert tag, avoid NSAIDs, alcohol
    • anticonvulsants: CNS depression, myelosuppression: infection and bleeding
      • assist with activity; protect airway, breathing; minimize invasive procedures
      • monitor seizure activity, CBC with diff, temperature, regional redness, swelling, or drainage
      • teaching: wear Medic-alert tag, avoid dangerous activity, wash hands, avoid crowds, need for follow-up care and testing
    • antidysrhythmics: new or more dangerous dysrhythmias, changes in BP
      • maintain F/E balance, SaO2 >95%, sinus rhythm; assist with position changes
      • monitor PFT, EKG, BP, pulse, SaO2, serum electrolytes, LOC
      • teaching: ask for help to stand, report irregular pulse, technique for counting pulse
    • antiinfective agents: renal and hepatic dysfunction
      • obtain cultures before administration, verify administration guidelines, screen for renal and hepatic dysfunction, allergy, nephrotoxic or hepatotoxic drugs
      • monitor RFT, LFT, jaundice, dark stool or urine, nausea and vomiting
      • report nausea, vomiting, dark stool or urine, jaundice; need for follow-up care and testing
    • loop, thiazide diuretics: circulatory collapse, myelosuppression, F/E imbalance, ototoxicity
      • verify infusion guidelines, B/P, serum electrolytes, and U/O before giving
      • monitor serum Na+ and K+, breath sounds, edema, BP, U/O
      • teaching: report palpitations, weakness, irregular pulse, decreased U/O, temperature
    • female hormones: thromboembolic disorders, increased risk of breast and endometrial cancer, hyperglycemia, hypercalcemia, depression, seizures
      • monitor peripheral perfusion, edema; leg pain, tenderness; serum Ca++, glucose
      • teaching: report lumps and abnormal bleeding, muscle twitching

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