THE ENDOCRINE SYSTEM
Health History
- Presenting problem: symptoms may include
- Change in appearance: hair, nails, skin (change in texture or pigmentation); change in size, shape, or symmetry of head, neck, face, eyes, or tongue
- Change in energy level
- Temperature intolerance
- Development of abnormal secondary sexual characteristics; change in sexual function
- Change in emotional state, thought pattern, or intellectual functioning
- Signs of increased activity of sympathetic nervous system (e.g., nervousness, palpitations, tremors, sweating)
- Change in bowel habits, appetite, or weight; excessive hunger or thirst
- Change in urinary pattern
- Life-style: any increased stress
- Past medical history: growth and development (any delayed or excessive growth); diabetes, thyroid disease, hypertension, obesity, infertility
- Family history: endocrine diseases, growth problems, obesity, mental illness
Physical Examination
- Check height, weight, body stature, and body proportions.
- Observe distribution of muscle mass, fat distribution, any muscle wasting.
- Inspect for hair growth and distribution.
- Check condition and pigmentation of skin; presence of striae.
- Inspect eyes for any bulging.
- Observe for enlargement in neck area and quality of voice.
- Observe development of secondary sex characteristics.
- Palpate thyroid gland (normally cannot be palpated): note size, shape, symmetry, any tenderness, presence of any lumps or nodules.
Laboratory/Diagnostic Tests
A variety of tests may be performed to measure the amounts of hormones present in the serum or urine in assessing pituitary, adrenal, and parathyroid functions; these tests will be referred to when appropriate under specific disorders of the endocrine system.
Thyroid Function
- Serum studies: nonfasting blood studies (no special preparation necessary)
- Serum T4 level: measures total serum level of thyroxine
- Serum T3 level: measures serum triiodothyronine level
- TSH: measurement differentiates primary from secondary hypothyroidism
- Radioactive iodine uptake (RAIU)
- Administration of 123I or 131I orally; measurement by a counter of the amount of radioactive iodine taken up by the gland after 24 hours
- Performed to determine thyroid function; increased uptake indicates hyperactivity; minimal uptake may indicate hypothyroidism
- Nursing care
- Take thorough history; thyroid medication must be discontinued 7-10 days prior to test; medications containing iodine, cough preparations, excess intake of iodine-rich foods, and tests using iodine (e.g., IVP) can invalidate this test.
- Assure client that no radiation precautions are necessary.
- Thyroid scan
- Administration of radioactive isotope (orally or IV) and visualization by a scanner of the distribution of radioactivity in the gland
- Performed to determine location, size, shape, and anatomic function of thyroid gland; identifies areas of increased or decreased uptake; valuable in evaluating thyroid nodules
- Nursing care: same as RAIU
Pancreatic Function
- Fasting blood sugar: measures serum glucose levels; client fasts from midnight before the test
- Two-hour postprandial blood sugar: measurement of blood glucose 2 hours after a meal is ingested
- Fast from midnight before test
- Client eats a meal consisting of at least 75 g carbohydrate or ingests 100 g glucose
- Blood drawn 2 hours after the meal
- Oral glucose tolerance test: most specific and sensitive test for diabetes mellitus
- Fast from midnight before test
- Fasting blood glucose and urine glucose specimens obtained
- Client ingests 100 g glucose; blood sugars are drawn at 30 and 60 minutes and then hourly for 3-5 hours; urine specimens may also be collected
- Diet for 3 days prior to test should include 200 g carbohydrate and at least 1500 kcal/day
- During test, assess the client for reactions such as dizziness, sweating, and weakness
- Glycosylated hemoglobin (hemoglobin A1c) reflects the average blood sugar level for the previous 100-120 days. Glucose attaches to a minor hemoglobin (A1c). This attachment is irreversible.
- Fasting is not necessary.
- Excellent method to evaluate long term control of blood sugar.
Wednesday, July 25, 2007
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This entry was posted on Wednesday, July 25, 2007
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